Sex Differences in Hospitalizations in the 6 Months Before a Diagnosis of Transthyretin Amyloid Cardiomyopathy

Chun Shing Kwok; Adnan I. Qureshi; Richard P. Steeds; Gregg C Fonarow; Biykem Bozkurt; Marianna Fontana; Julian D. Gillmore; William E. Moody

doi:10.1016/j.jacadv.2026.102627

March 1, 2026JACC AdvancesOpen Access

Sex Differences in Hospitalizations in the 6 Months Before a Diagnosis of Transthyretin Amyloid Cardiomyopathy

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Key Points

To examine how sex influences missed opportunities for early diagnosis of transthyretin amyloid cardiomyopathy (ATTR-CM).
Analysis of hospital records to assess hospitalization trends
Comparison of hospitalization rates between sexes before ATTR-CM diagnosis
Evaluation of diagnostic procedures employed prior to diagnosis
Identified significant sex differences in hospitalization rates prior to ATTR-CM diagnosis
Highlighted missed opportunities for earlier detection in one sex compared to another
Provided insights into diagnostic trends and barriers in healthcare

Implication

Research uncovers sex differences affecting missed opportunities for diagnosing transthyretin amyloid cardiomyopathy in prior hospitalizations.

Abstract

The influence of sex on the extent of missed opportunities for early diagnosis of transthyretin amyloid cardiomyopathy (ATTR-CM) has not been characterized.

Discussion

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Cite This Study

Kwok et al. (2026) studied this question.

synapsesocial.com/papers/69c770c08bbfbc51511e0c5f https://doi.org/10.1016/j.jacadv.2026.102627

View Full Paper

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Sex Differences in Hospitalizations in the 6 Months Before a Diagnosis of Transthyretin Amyloid Cardiomyopathy

Key Points

Implication

Abstract

Discussion

Cite This Study

Sex Differences in Hospitalizations in the 6 Months Before a Diagnosis of Transthyretin Amyloid Cardiomyopathy

Key Points

Implication

Abstract

Discussion

Cite This Study

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