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Comprehensive experiment reveals the structure of santonic acid in organic chemistry coursework, highlighting an enquiry-based approach.
In this paper we describe a new comprehensive laboratory experiment based on a chemical transformation of santonin. The experiment is designed as a puzzle-solving exercise for advanced undergraduate organic chemistry courses and consists of the structure elucidation of santonic acid, the product obtained by the action of strong alkalis on santonin. An enquiry-based approach helps the students achieve this goal by combining their knowledge of organic chemistry and spectroscopy together with mechanistic thinking.
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Pellegrinet et al. (2002) studied this question.
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