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March 28, 2026The Chemical Educator

An Undergraduate Organic Chemistry Laboratory Experiment

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Authors

KOKenneth J. O’Connor

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Overview

An experiment demonstrates the use of thin layer chromatography to monitor reactions in an inert atmosphere, enhancing student skills.

Key Points

  • The research aims to enhance undergraduate laboratory education by incorporating thin layer chromatography in reactions conducted under a gaseous atmosphere.
  • Developed a hydrogenation experiment using 5% Pd/C for unsaturated esters.
  • Students learned sampling techniques with a 16 gauge needle and 30 µL micropipette during pre-lab.
  • Utilized methyl trans-cinnamate and dimethyl fumarate as alkenes in the experiment.
  • Student yields ranged from 50-90%, with an average yield of approximately 70-75%.
  • Students effectively learned to use TLC to monitor reactions in gas atmospheres.

Cite This Study

Kenneth J. O’Connor (2013) studied this question.

synapsesocial.com/papers/69c771348bbfbc51511e1191https://doi.org/10.1333/s00897132509a
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