Laboratory exercise synthesizes quaterthiophene using cross-coupling, highlighting practical skills in organic chemistry.
A practical undergraduate student laboratory exercise, synthesis of organic semiconductor material, quaterthiophene, using Suzuki-Miyaura cross-coupling approach is presented with detailed instructions. In this experiment, students will learn to recognize the basic needs for this class of coupling reaction, to work with inert atmosphere using a balloon technique, and to do relatively demanding recrystallization procedure. The progress of the reaction will be monitored by using thin layer chromatography (TLC) and students will learn to make conclusions when to finish the reaction. In addition, rotary evaporation, liquid-liquid extraction, and vacuum filtration techniques are recalled. The product is analyzed using 1H NMR and UV-vis spectrometers.
No takes yet. Share an insight, caveat, or question.
Juha P. Heiskanen (2014) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: