Cumulative defined daily doses enables objective assessment of treatment intensity and outcome prediction in immunoglobulin G4–related disease and its subtypes

Key Points

• The research aims to evaluate treatment intensity and predict outcomes in immunoglobulin G4-related disease using cumulative defined daily doses.
• Utilized cumulative defined daily doses (cDDD) for assessment.
• Focused on distinct proliferative and fibrotic phenotypes.
• Analyzed treatment responses and risks.
• cDDD successfully enabled objective evaluation of treatment intensity.
• Higher treatment intensities correlated with differential treatment responses.
• Findings support a precision medicine approach in managing IgG4-related disease.