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March 28, 2026Brain Sciences0 citationsOpen Access

Effects of Rhythmic Auditory Stimulation Using Sensory Feedback-Based Wearable Devices on the Gait and Balance in Patients with Parkinson’s Disease: A Systematic Review and Meta-Analysis

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JKJu-Hak KimMLMyung Ho LeeMKMyoung-Kwon Kim

Key Points

  • This review aims to evaluate the impact of rhythmic auditory stimulation via wearable devices on gait and balance in Parkinson's disease.
  • Conducted a systematic review and meta-analysis following PRISMA 2020 guidelines.
  • Performed literature searches across five databases (PubMed, Embase, Cochrane, Scopus, Web of Science).
  • Selected eleven randomized controlled trials (RCTs) meeting inclusion criteria.
  • Evaluated study quality using the PEDro scale and ROB-2.
  • Used Review Manager 5.4 for statistical analysis, focusing on means, standard deviations, and effect sizes.
  • Wearable rhythmic auditory stimulation significantly improved gait speed (SMD = 0.49, p < 0.05).
  • Balance ability also significantly improved (SMD = 0.40, p < 0.05).
  • No significant differences were found for gait pattern, FOG-Q, or UPDRS-III.
  • The analysis showed low heterogeneity and minimal publication bias.
  • The average PEDro score was 7.33, indicating moderate-to-high methodological quality.

Abstract

Background: This paper presents a systematic review and meta-analysis to identify the effects of Rhythmic Auditory Stimulation (RAS) delivered via wearable devices on the gait and balance in patients with Parkinson’s disease. Method: The PICO criteria were established according to the PRISMA 2020 guidelines, and literature searches were performed across five databases covering studies published between 2015 and 2025: PubMed, Embase, Cochrane, Scopus, and Web of Science. After applying the inclusion criteria, eleven randomized controlled trials (RCTs) were selected. The quality of the studies was evaluated using the PEDro Scale and ROB-2. Statistical analyses were performed using Review Manager 5.4 based on the number of samples, means, and standard deviations to calculate the effect sizes. Result: The analysis results showed that wearable RAS significantly improved the gait speed (SMD = 0.49, p < 0.05) and balance ability (SMD = 0.40, p < 0.05), while no significant differences in the gait pattern, FOG-Q, or UPDRS-III were observed. The heterogeneity among studies was low, and the funnel plots were distributed symmetrically, indicating minimal publication bias. The average PEDro score was 7.33, suggesting moderate-to-high methodological quality. Conclusion: wearable RAS was identified as an evidence-based intervention effective in improving the gait speed and balance in patients with Parkinson’s disease.

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Cite This Study

Kim et al. (2026) studied this question.

synapsesocial.com/papers/69c772158bbfbc51511e2548https://doi.org/10.3390/brainsci16040359
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