Traumatic Occlusion Exacerbates Bone Resorption by Modifying Gene Expression in the Bone Tissue of Ligature‐Induced Periodontitis in Mice

Key Points

• To determine how traumatic occlusion affects bone resorption and gene expression in ligature-induced periodontitis.
• Used a mouse model with ligature-induced periodontitis.
• Assessed the impact of traumatic occlusion on bone resorption.
• Analyzed gene expression related to inflammation in bone tissues.
• Traumatic occlusion significantly increased bone resorption rates.
• Enhanced expression of inflammation-related genes was noted in bone with periodontitis.
• Traumatic occlusion did not lead to significant bone loss independently.