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March 28, 2026npj Antimicrobials and Resistance2 citationsOpen Access

Artificial intelligence for early detection and risk prediction of antimicrobial resistance in aquatic ecosystems

WCWilliam Calero-CáceresUniversidad Técnica de AmbatoRTRonan Adler TavellaFundação de Apoio à Universidade Federal de São PauloFSFábio Parra SelleraUniversidade de São Paulo

Key Points

  • The aim is to improve early detection and risk prediction of antimicrobial resistance in aquatic ecosystems using AI.
  • Integration of artificial intelligence with metadata for analysis.
  • Characterization of antimicrobial resistance genes and resistome profiles.
  • Utilization of spatiotemporal predictive models combining omics and environmental data.
  • Focus on real-time monitoring and risk assessment.
  • Novel antimicrobial resistance genes were identified.
  • Resistome profiles were characterized effectively.
  • Predictive models showed improved accuracy in forecasting AMR dynamics.
  • Strengthened capacity in predictive monitoring was noted.

Abstract

Aquatic environments are key reservoirs and dissemination pathways of antimicrobial resistance (AMR). However, current water-based surveillance remains fragmented and inefficient for the timely detection of emerging threats. Integrating artificial intelligence with embedded metadata provides a powerful pathway to identify novel antimicrobial resistance genes, characterize resistome profiles, and predict AMR dynamics in real-time by combining omics, environmental, and hydrological data into spatiotemporal predictive models. Successful implementation of this framework will require robust governance, ethical safeguards, and capacity building to support predictive AMR monitoring aligned with the One Health approach.

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Cite This Study

Calero-Cáceres et al. (2026) studied this question.

synapsesocial.com/papers/69c7724e8bbfbc51511e2b39https://doi.org/10.1038/s44259-026-00192-w
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