Advances in Severe Traumatic Brain Injury Complicated With Intestinal Failure

Patients with severe traumatic brain injury have a high incidence of intestinal failure because of systemic stress response and gut-brain axis dysfunction, which is closely related to poor prognosis. Focusing on severe traumatic brain injury complicated with intestinal failure, this article reviews its definition and classification, main risk factors (gastrointestinal dysfunction, intestinal barrier injury, drug effects, etc.), clinical assessment tools, and therapeutic intervention measures centered on enteral nutrition. It emphasizes the important role of individualized plans in improving patients' nutritional status, protecting gut mucosal integrity, and reducing the incidence of complications, so as to provide a reference for clinical standardized diagnosis and treatment.