Case report demonstrates durable remission of melasma using laser therapy and topical JAK inhibition, suggesting new treatment options.
This case illustrates the potential clinical value of combining pigment-targeted picosecond laser therapy with topical JAK inhibition and visible light-specific photoprotection for recalcitrant melasma. The durable remission achieved supports further investigation into anti-inflammatory and photoreactive pathway modulation as adjunctive strategies in melasma management.
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Ashkanani et al. (2026) studied this question.
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