Narrative review explores safety and efficacy of novel drug and gene therapies in lupus, suggesting effective options.
Systemic lupus erythematosus (SLE) poses diagnostic and management challenges to physicians given its protean manifestations and complex immune dysregulation. Numerous drugs are used in the management of lupus with a plethora under investigation for more effective, safe, and targeted therapies. This narrative review explores recent literature on the safety and efficacy multiple drug classes and gene therapy under investigation in the management of SLE. The findings in this review detail which new candidate drug and gene therapies are showing efficacy and safety in SLE management, and which are not.
No takes yet. Share an insight, caveat, or question.
Loncharich et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: