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March 29, 2026American Journal of Neuroradiology0 citationsOpen Access

Smokers with Large Vessel Occlusion Stroke Show Poor Leptomeningeal Collaterals

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HBHakim BaazaouiFMFrancesco MorraLOLukas Bastian Otto

Key Points

  • To investigate the relationship between smoking history and leptomeningeal collateral status in patients with large vessel occlusion stroke.
  • Utilized digital subtraction angiography (DSA) for assessment
  • Evaluated collateral status in stroke patients with a history of smoking
  • Compared findings with prior studies using CTA
  • Significant association found between positive smoking history and worse collateral status
  • Contradicts previous studies suggesting smokers have better outcomes (smokers' paradox)

Abstract

DSA-based assessment demonstrated a significant association between positive smoking history and worse collateral status. These findings contradict prior CTA-based studies and the "smokers' paradox" hypothesis.

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Cite This Study

Baazaoui et al. (2026) studied this question.

synapsesocial.com/papers/69c8c15ade0f0f753b39bd66https://doi.org/10.3174/ajnr.a9320
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