The study aims to investigate the protective effects of rosmarinic acid against ototoxicity caused by radiotherapy.
Applied rosmarinic acid both systemically and locally.
Conducted histopathological examinations to assess tissue changes.
Utilized objective audiological methods to evaluate hearing function.
Rosmarinic acid significantly reduces signs of ototoxicity in histopathological findings.
Objective audiological tests show improved hearing in treated subjects compared to controls.
Abstract
Rosmarinic acid protects against radiotherapy-induced ototoxicity when applied both systemically and locally, as confirmed by histopathological examination and objective audiological methods.