An optimized MP2RAGE protocol improves spinal cord imaging and lesion detection efficiency in multiple sclerosis, suggesting a valuable tool for clinical research.
We present a 3T spinal cord-optimized MP2RAGE protocol capable of covering the entire cervical spinal cord in approximately 5 minutes. This protocol offers high tissue CNR-fundamental for area quantification-, as well as lesion-detection efficacy comparable to that of established methods. Therefore, such a single MRI protocol could be an efficient approach for conducting clinical research.
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Papinutto et al. (2026) studied this question.
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