Is Ready‐To‐Use AbobotulinumtoxinA More Effective Than OnabotulinumtoxinA for Glabellar Lines? A Randomized, Controlled, Triple‐Blinded Clinical Trial

Jacqueline Rosa Gonçalves; Lígia Figueiredo Valesan; Ana Claudia Laureano Navarro Shishido; Alfonso Sánchez‐Ayala; Ana Claudia Carbone; Mariana Barbosa Câmara‐Souza; Giancarlo De la Torre Canales

doi:10.1111/jocd.70816

March 26, 2026Journal of Cosmetic DermatologyOpen Access

Is Ready‐To‐Use AbobotulinumtoxinA More Effective Than OnabotulinumtoxinA for Glabellar Lines? A Randomized, Controlled, Triple‐Blinded Clinical Trial

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Key Points

This trial aims to compare the effectiveness and safety of Ready-To-Use AbobotulinumtoxinA against OnabotulinumtoxinA for treating glabellar lines.
Randomized, controlled, triple-blinded design
Administration of RTUaboBoNT-A and OnaBoNT-A to participants
Assessment of efficacy, durability, and safety profiles post-treatment
RTUaboBoNT-A shows similar efficacy to OnaBoNT-A
Durability of effects is comparable between both treatments
Minor differences noted in patient satisfaction and injection discomfort

Abstract

The RTUaboBoNT-A demonstrated similar efficacy, durability, and safety profile to OnaBoNT-A for the treatment of glabellar lines. With minor differences in satisfaction and injection disconfort.

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Gonçalves et al. (2026) studied this question.

synapsesocial.com/papers/69c8c1f4de0f0f753b39c2f6 https://doi.org/10.1111/jocd.70816

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Is Ready‐To‐Use AbobotulinumtoxinA More Effective Than OnabotulinumtoxinA for Glabellar Lines? A Randomized, Controlled, Triple‐Blinded Clinical Trial

Key Points

Abstract

Discussion

Cite This Study

Is Ready‐To‐Use AbobotulinumtoxinA More Effective Than OnabotulinumtoxinA for Glabellar Lines? A Randomized, Controlled, Triple‐Blinded Clinical Trial

Key Points

Abstract

Discussion

Cite This Study

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