Case report documents vellus-like hair growth on distal thumb skin in VKHD, highlighting a rare manifestation.
Rationale: This report describes a rare integumentary finding – vellus-like hair growth on the glabrous palmar skin – in a patient with VKHD. To our knowledge, such a manifestation has not been previously documented. Patient concerns: A 25-year-old woman presented with unusual hair growth on the radial and palmar surface of the distal thumb, emerging 2 years after the initial diagnosis of VKHD. Diagnoses: Previously diagnosed VKHD with recurrent episodes of auditory symptoms and rare occurrence of short, fine vellus-like hairs at a glabrous skin site. Interventions: She was managed with low-dose oral prednisolone (5–10 mg/d), which alleviated auditory symptoms. Dermatology consultation confirmed the unusual hair growth pattern. Outcomes: The hair growth recurred twice within a span of 2 years, lasting 4 to 6 weeks each time, and did not recur thereafter. Lessons: The presence of hair follicles or vellus-like hairs on glabrous skin is exceedingly rare. This observation expands the spectrum of integumentary manifestations associated with VKHD and warrants documentation for future reference.
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Amir et al. (2026) studied this question.
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