Comparative Analysis of Kidney and Simultaneous Pancreas–Kidney Transplantation: Long-Term Outcomes in Type 1 Diabetic Patients with End-Stage Kidney Disease
Comparative analysis shows no survival benefit from simultaneous pancreas-kidney transplants in type 1 diabetes patients.
Key Points
To analyze long-term outcomes of kidney transplantation alone versus simultaneous pancreas-kidney transplantation in type 1 diabetic patients with end-stage kidney disease.
Analyzed data from 101 patients who received kidney transplants (KTx) and 93 who received simultaneous pancreas-kidney transplants (SPK).
Both groups underwent minimal follow-up of 5 years post-transplantation.
Compared survival rates, complications, and kidney function between the two transplant groups.
No significant difference in recipient, kidney graft, or death-censored kidney graft survival between KTx and SPK.
SPK recipients had a shorter total diabetes duration compared to KTx recipients (28.1 vs. 34.9 years).
KTx group exhibited higher rates of myocardial infarction, limb amputation, and proteinuria compared to SPK.
Lower estimated glomerular filtration rate was observed in KTx recipients.