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March 29, 2026Artificial OrgansOpen Access

Predictors of Brain Infarction in Pediatric Patients During Extracorporeal Membrane Oxygenation

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Authors

RIRiccardo IacobelliTFThomas FuxSSSara Wood Schalling

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Overview

A single-center cohort study identifies predictors of brain infarction in pediatric patients on ECMO, suggesting the need for improved monitoring.

Key Points

  • This research aims to determine the incidence and predictors of brain infarction (BI) in pediatric patients undergoing ECMO treatment.
  • Conducted a retrospective cohort study at a tertiary center.
  • Included patients aged 29 days to < 18 years who underwent ECMO from January 2010 to October 2023.
  • Analyzed predictors of BI using logistic regression.
  • Brain infarction occurred in 51 out of 179 patients (28%).
  • Venoarterial ECMO and higher pre-ECMO arterial lactate were identified as independent predictors of BI.
  • 30-day mortality for patients with BI was 67%, compared to 15% for those without BI.

Cite This Study

Iacobelli et al. (2026) studied this question.

synapsesocial.com/papers/69c8c324de0f0f753b39db42https://doi.org/10.1111/aor.70115
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