Findings reveal that MSCs from reproductive tissues improve fertility by linking follicular activation and endometrial remodeling, suggesting important implications for infertility treatments.
These data suggest that MSCs derived from reproductive tissues, particularly endometrial origin, may restore fertility in POI by linking follicular activation to endometrial remodeling and support the translational development of MSC therapies that address both follicular depletion and uterine competence in infertility.
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Borutinskaitė et al. (2026) studied this question.
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