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March 29, 2026BJOG An International Journal of Obstetrics & Gynaecology

Association Between Parity and Subclinical Left Ventricular Dysfunction in Healthy Pregnant Women: A Prospective Cross‐Sectional Study

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Why the study?

Does higher parity associate with subclinical left ventricular dysfunction in healthy pregnant women?

Population

Healthy pregnant women

Comparison

Higher parity vs lower parity

Design

Prospective cross-sectional study

Key result

Higher parity in healthy pregnant women is independently associated with reduced myocardial strain detected by global longitudinal strain, despite preserved ejection fraction.

Authors

ÖKÖmer KümetFPFuat PolatİUİpek Uzaldı

Discussion

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Overview

May warrant strain assessment beyond EF in higher-parity pregnancies; hypothesis-generating for long-term CV risk.

Key Points

  • To investigate the association between parity and subclinical left ventricular dysfunction in healthy pregnant women.
  • Prospective cross-sectional study design
  • Measured myocardial strain using global longitudinal strain (GLS)
  • Focused on healthy pregnant women with varying parity
  • Compared GLS values with preserved ejection fraction
  • Higher parity is linked to reduced myocardial strain detected by GLS
  • GLS values, while within normal ranges, trend lower with each additional pregnancy
  • Findings suggest cumulative haemodynamic effects on cardiac structure and function

Structured PICO

Does higher parity associate with subclinical left ventricular dysfunction in healthy pregnant women?

P
Population
Healthy pregnant women
I
Intervention
Higher parity
O
Outcome
Subclinical left ventricular dysfunction (reduced myocardial strain detected by GLS)surrogate

Higher parity is associated with cumulative subclinical reductions in left ventricular myocardial strain in healthy pregnant women, suggesting cumulative hemodynamic effects.

Cite This Study

Kümet et al. (2026) studied this question. Higher parity in healthy pregnant women is independently associated with reduced myocardial strain detected by global longitudinal strain, despite preserved ejection fraction.

synapsesocial.com/papers/69c8c35cde0f0f753b39e1b4https://doi.org/10.1111/1471-0528.70232
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