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March 29, 2026European Journal of Clinical Investigation1 citationsOpen Access

A nomogram for predicting in‐hospital death in a multinational cohort of patients with takotsubo syndrome

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YCYuyi ChenACAmanda ChangFCFangyuan Cheng

Key Result

A nomogram composed of BMI, CKD, neurologic disorders, chest pain, cardiogenic shock, low SBP, and abnormal WBC helps predict in-hospital death in patients with takotsubo syndrome.

Key Points

  • The aim is to create a nomogram that predicts in-hospital death in patients with takotsubo syndrome using specific clinical indicators.
  • Developed a nomogram incorporating BMI, chronic kidney disease (CKD), and neurologic disorders.
  • Analyzed data from a multinational cohort of patients with takotsubo syndrome.
  • Evaluated the predictive ability of the nomogram based on various clinical parameters.
  • Identified key predictors of in-hospital death including chest pain, cardiogenic shock, low SBP, and abnormal WBC levels.
  • Showed that the nomogram effectively predicts mortality risk in hospitalized takotsubo patients.

Structured PICO

Can a nomogram composed of clinical variables predict in-hospital death in patients with takotsubo syndrome?

P
Population
Patients with takotsubo syndrome (TTS)
I
Intervention
Nomogram composed of BMI, CKD, neurologic disorders, chest pain, cardiogenic shock, low SBP and abnormal WBC
O
Outcome
In-hospital deathhard clinical

A 7-variable clinical nomogram can help predict the risk of in-hospital death in patients with takotsubo syndrome.

Abstract

The nomogram, composed of BMI, CKD, neurologic disorders, chest pain, cardiogenic shock, low SBP and abnormal WBC, helps predict in-hospital death in TTS patients.

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Cite This Study

Chen et al. (2026) studied this question. A nomogram composed of BMI, CKD, neurologic disorders, chest pain, cardiogenic shock, low SBP, and abnormal WBC helps predict in-hospital death in patients with takotsubo syndrome.

synapsesocial.com/papers/69c8c384de0f0f753b39e4f4https://doi.org/10.1111/eci.70190
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A Nomogram for Predicting In-Hospital Mortality in Patients with Takotsubo Syndrome2021
  2. 2Development and validation of a prognostic nomogram for Takotsubo syndrome patients in the intensive care units: a retrospective cohort study2023 · 3 citations
  3. 3Importance of hospital and clinical factors for early mortality in Takotsubo syndrome: Insights from the Swedish Coronary Angiography and Angioplasty Registry2024 · 1 citations
  4. 4Observed Clinical, Laboratory, and Echocardiographic Parameters in Takotsubo Syndrome Patients with Mortality and Decreased Ejection Fraction During Initial Hospital Admission2018 · 2 citations
  5. 5Importance of hospital and clinical factors for early mortality in Takotsubo syndrome: Insights from the Swedish Coronary Angiography and Angioplasty Registry2024