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March 29, 2026Food & Function0 citations

Acid hydrolysis of jaboticaba ( Myrciaria jaboticaba ) peel and seeds powder increases urolithins excretion in a cross-over clinical trial with normoweight volunteers.

RBRafael BizareloKIKim Ohanna Pimenta InadaDPDaniel Perrone

Key Points

  • This research aims to assess the effects of acid hydrolysis of jaboticaba on urolithins excretion.
  • Conducted a crossover clinical trial
  • Involved normoweight volunteers
  • Applied acid hydrolysis to jaboticaba peel and seeds powder
  • Measured urolithins levels post-intervention
  • Increased urolithins excretion observed after treatment
  • Enhanced bioavailability of ellagitannins noted
  • Positive correlation between acid hydrolysis and urolithin levels

Abstract

Ellagitannins are phenolic compounds found in various plant sources, including jaboticaba ( Myrciaria jaboticaba ), and exhibit beneficial health effects primarily through urolithins, their gut-derived metabolites. However, ellagitannins bioavailability and metabolism is...

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Cite This Study

Bizarelo et al. (2026) studied this question.

synapsesocial.com/papers/69c8c3bdde0f0f753b39ec6ahttps://doi.org/10.1039/d5fo04952k
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The effect of jaboticaba peel and seed powder intake for three weeks on urolithin metabotype and excretion in normoweight and overweight/obese Brazilians2026 · 1 citations
  2. 2Strawberry Processing Does Not Affect the Production and Urinary Excretion of Urolithins, Ellagic Acid Metabolites, in Humans2011 · 98 citations
  3. 3Effects of drying methods and solvent extraction on quantification of major bioactive compounds in pomegranate peel waste using HPLC2022 · 46 citations
  4. 4Bioavailability of Anthocyanins and Ellagitannins Following Consumption of Raspberries by Healthy Humans and Subjects with an Ileostomy2010 · 280 citations
  5. 5Food processing strategies to enhance phenolic compounds bioaccessibility and bioavailability in plant-based foods2017 · 371 citations