Abstract All-cause mortality is a population health indicator of the combined impact of biological, behavioral, social, and healthcare-related factors. We used data from 3, 803 participants (1, 947 women, 51. 2%; aged 20 to 81 years) of the population-based Study of Health in Pomerania (SHIP-START-0, 1997–2001), with a median follow-up duration of 20. 2 years. Sex-stratified cox proportional hazard models were used to estimate associations between socioeconomic, lifestyle, anthropometric, and cardiovascular risk factors with all-cause mortality. During the 70, 982 person-years, 1, 029 deaths (641 men and 388 women) were determined as all-cause mortality. In men, type 2 diabetes (hazard ratio HR = 1. 83 95% confidence interval CI: 1. 48 to 2. 25; p < 0. 001), living without a partner (HR = 1. 78 95% CI: 1. 41 to 2. 24; p < 0. 001), being a current smoker (HR = 1. 76 95% CI: 1. 41 to 2. 20; p < 0. 001), older age (HR per year = 1. 10 95% CI: 1. 10 to 1. 11; p < 0. 001) and elevated hs-CRP (HR per mmol/l = 1. 07 95% CI: 1. 03 to 1. 11; p < 0. 001) where significantly associated with increased all-cause mortality. In women, just type 2 diabetes (HR = 1. 70 95% CI: 1. 28 to 2. 15; p < 0. 001) and elevated hs-CRP (HR per mmol/l = 1. 07 95% CI: 1. 03 to 1. 12; p < 0. 001) where significantly associated with increased all-cause mortality. Type 2 diabetes and inflammation were linked to higher all-cause mortality in both sexes, whereas being without a partner, current smoking, and older age were significant risk factors specifically for men.
Lederman et al. (Sat,) studied this question.
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