Abstract: A 60-year-old woman with previous lung adenocarcinoma had bicytopenia and fragmented red blood cells (schistocytes) on a peripheral blood smear, indicating microangiopathic hemolytic anemia (MAHA). A bone marrow biopsy revealed metastatic adenocarcinoma. The identification of cancer-associated MAHA highlighted the significance of peripheral smear evaluation in distinguishing it from thrombotic thrombocytopenic purpura and targeting therapies toward underlying malignancy management.
Majed Abdul Basit Momin (2026) studied this question.