Case report of lung adenocarcinoma reveals microangiopathic hemolytic anemia, indicating the need for targeted therapies.
A 60-year-old woman with previous lung adenocarcinoma had bicytopenia and fragmented red blood cells (schistocytes) on a peripheral blood smear, indicating microangiopathic hemolytic anemia (MAHA). A bone marrow biopsy revealed metastatic adenocarcinoma. The identification of cancer-associated MAHA highlighted the significance of peripheral smear evaluation in distinguishing it from thrombotic thrombocytopenic purpura and targeting therapies toward underlying malignancy management.
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Majed Abdul Basit Momin (2026) studied this question.
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