This vignette-based study evaluates a new sepsis diagnostic's impact on clinical decision making in the emergency department, suggesting improved patient care outcomes.
Objectives: Sepsis is a complex pathogen-host interaction that traditional laboratories do not easily detect.A test that rapidly assesses immune dysregulation could improve early diagnosis and clinical decision making.This study evaluates ease of application of a new host-response sepsis diagnostic test (IntelliSep; Cytovale, Inc) and its ability to affect decision making, risk stratification, and diagnostic efficacy in the emergency department (ED).Methods: This was a case vignette-based, randomized, multisite decision-impact study.
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Sheybani et al. (2026) studied this question.
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