Sulfatase 2 up‐regulates glypican 3, promotes fibroblast growth factor signaling, and decreases survival in hepatocellular carcinoma†

Jinping Lai; Dalbir S. Sandhu; Chunrong Yu; Tao Han; Catherine D. Moser; Kenard K. Jackson; Rubén Bonilla Guerrero; Ileana Aderca; Hajime Isomoto; Megan Garrity-Park; Hongzhi Zou; Abdirashid M. Shire; David M. Nagorney; Schuyler O. Sanderson; Alex A. Adjei; Ju‐Seog Lee; Snorri S. Thorgeirsson; Lewis R. Roberts

doi:10.1002/hep.22202

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Abstract

In contrast to the tumor suppressor effect of SULF1, SULF2 has an oncogenic effect in HCC mediated in part through up-regulation of FGF signaling and GPC3 expression.

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Lai et al. (2008) studied this question.

synapsesocial.com/papers/69cac1a4f743a50aa607906e https://doi.org/10.1002/hep.22202

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Sulfatase 2 up‐regulates glypican 3, promotes fibroblast growth factor signaling, and decreases survival in hepatocellular carcinoma†

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Abstract

Discussion

Cite This Study

Sulfatase 2 up‐regulates glypican 3, promotes fibroblast growth factor signaling, and decreases survival in hepatocellular carcinoma†

Ask about this paper

Abstract

Discussion

Cite This Study

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