Key result
GP audit and feedback linked to ~67% higher LDL-C target attainment in high-risk patients.
Why the study?
Does an audit and feedback intervention for general practitioners improve lipid management and LDL-C target attainment in high cardiovascular risk patients?
Observational
Does an audit and feedback intervention for general practitioners improve lipid management and LDL-C target attainment in high cardiovascular risk patients?
Absolute Event Rate: 14.5% vs 8.7%
An audit and feedback intervention for general practitioners significantly improved clinical data recording and LDL-C target attainment in high-risk patients.
Introduction Cardiovascular diseases remain the leading cause of morbidity and mortality worldwide. Low-density lipoprotein cholesterol (LDL-C) plays a central role in atherogenesis and cardiovascular events. In real-world primary care, many patients at high and very-high cardiovascular risk (HCVR) do not achieve recommended LDL-C targets. Objectives This study evaluated whether an audit and feedback (A&F) intervention could improve lipid management in HCVR patients managed in general practice. Methods We conducted a retrospective–prospective observational study involving general practitioners (GPs). GPs were classified as active, participating in A&F training and feedback sessions, or controls, contributing data only. Patient-level data were extracted from electronic medical records across three 18-month observation periods (T0, T1, and T2). Active GPs received tailored performance reports and educational sessions after T0 and T1. Main outcomes included completeness of clinical data recording, LDL-C target attainment (<70 mg/dL), lipid-lowering treatment patterns, and treatment adherence. Results Compared with baseline, active GPs showed significant improvements in the recording of LDL-C (+18.3%), HbA1c (+5.7%), body mass index (+17.1%), smoking status (+4.4%), and alcohol consumption (+14.4%). LDL-C target attainment increased from 6.1% at T0 to 14.5% at T2, exceeding the proportion observed in controls at T2 (8.7%). The use of lipid-lowering therapy among active GPs increased from 48.9% at T0 to 61.3% at T2, while high-intensity therapy increased from 9.1% to 17.6%. Treatment adherence improved over time, with a higher proportion of patients adherent to high-intensity therapy and a reduction in non-adherent low-intensity therapy. Conclusion An audit and feedback intervention supported by a multidisciplinary team improved data completeness and lipid management in high-risk patients in the primary care setting.
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Rottura et al. (2026) conducted an observational in High and very-high cardiovascular risk (HCVR). Audit and feedback (A&F) intervention vs. Controls (contributing data only) was evaluated on LDL-C target attainment (<70 mg/dL). An audit and feedback intervention for general practitioners increased LDL-C target attainment (<70 mg/dL) in high-risk patients to 14.5% compared to 8.7% in controls.
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