Symptom Burden and Healthcare Resource Use in Patients With Claudin 18.2–Positive, HER2-Negative, Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma: A Retrospective Review
Retrospective review reveals high symptom burden and healthcare resource use in patients with advanced gastric cancer.
Key Points
To describe the disease-related symptoms and healthcare resource utilization in patients with claudin 18.2-positive, HER2-negative advanced gastric adenocarcinoma.
Conducted a retrospective review of adult patients with claudin 18.2-positive gastric adenocarcinoma.
Assessed outcomes from diagnosis to follow-up end date.
Collected data on symptoms and healthcare resource utilization.
Sixty-two patients included with a mean age of 61.3 years.
All patients reported an average of 7.2 disease-related symptoms at diagnosis.
Common symptoms included weight loss (74.2%) and abdominal pain (66.1%).
95.2% of patients at 6-month follow-up reported at least one symptom.
A mean of 3.4 outpatient visits per patient per month was noted.
Cite This Study
Sewastjanow-Silva et al. (2026) studied this question.