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April 1, 2026Journal of Advanced Research in Natural and Applied SciencesOpen Access

Rapid and Selective Cefuroxime Sensing via Gold Nanoparticle-Enhanced MIP-based Electrochemical Sensors

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Authors

ACAhmet CetinkayaSÖSibel A. Özkan

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Overview

Development of a sensor utilizing gold nanoparticles for Cefuroxime detection, indicating practical application in pharmaceuticals.

Key Points

  • This research aims to develop a highly sensitive and selective sensor for cefuroxime detection using molecularly imprinted polymers and gold nanoparticles.
  • Developed a molecularly imprinted polymer-based electrochemical sensor.
  • Enhanced sensor with gold nanoparticles to increase surface area.
  • Electropolymerized 1H-indazole-5-boronic acid and aniline on a glassy carbon electrode.
  • Conducted electrochemical impedance spectroscopy, cyclic voltammetry, and scanning electron microscopy for characterization.
  • Validated sensor performance using biological samples and injectable powder formulations.
  • Achieved a limit of detection of 1.59 × 10-12 M for cefuroxime.
  • Demonstrated excellent linearity in the range of 1.00 × 10-11 M to 3.75 × 10-10 M.
  • Maintained high selectivity for cefuroxime over other closely related cephalosporins.
  • Confirmed robustness and applicability of the sensor in real samples.

Cite This Study

Cetinkaya et al. (2026) studied this question.

synapsesocial.com/papers/69ccb62016edfba7beb87cf9https://doi.org/10.28979/jarnas.1870107
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Electrochemical Sensor Based on Molecularly Imprinted Polymer for Cefuroxime Detection in Biological and Environmental Samples2026
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