Introduction: Sexual dysfunction (SD) is a common yet underrecognized complication of chronic kidney disease, often beginning in the early stages and worsening as renal impairment progresses. Uremic toxins, coexisting comorbidities, anemia, endocrine disturbances, neuropathic and vascular complications, hyperparathyroidism, elevated prolactin, adverse drug reactions, and psychological stress are some of the multifactorial underlying causes. It has historically gotten little clinical attention, despite having a significant impact on quality of life. Renal transplant reverses many underlying contributors to SD, often leading to measurable gains in reproductive health and sexual well-being. Methods: Forty-seven male renal transplant recipients participated in this 1-year study, which used a prospective study design and was carried out at a single tertiary center facility. A comprehensive questionnaire was given to participants to evaluate their physical and mental health, sexual orientation, and socioeconomic circumstances. The International Index of Erectile Function (IIEF) was used to assess sexual functions. SPSS software, version 25.0, was used to conduct a statistical analysis of the data that was gathered. Results: The majority of patients were between the ages of 26 and 37 years, and the average age of participants at the time of renal transplantation was 33.31 ± 9.7 years. The mean length of time they had been receiving hemodialysis before the transplant was 17.2 ± 1.2 months. The majority of transplant recipients belonged to the upper middle socioeconomic class. Erectile function (EF) improved in 37 (78.7%) recipients, orgasmic function improved in 30 (63.8%) recipients, and sexual desire improved in 35 (74.4%) recipients after transplantation. Every one of the five IIEF domains showed a statistically significant improvement. Conclusion: According to this study, men with advanced kidney disease can significantly improve their sexual health through renal transplantation. Following the transplant, many participants reported improved sexual function, particularly in areas like EF and general satisfaction. Sexual function is improved by renal transplantation because it enhances psychological health and metabolic balance. Kidney transplantation is often offered to patients in their 40s and 50s, many of whom still desire a fulfilling sexual and reproductive life, particularly considering that typical graft survival ranges from 7 to 15 years.
Sarkar et al. (Thu,) studied this question.