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April 1, 2026Journal of Clinical MedicineOpen Access

From Strength to Dexterity: Clinically Meaningful Recovery of Upper Limb in Individuals with Cervical Spinal Cord Injury

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Authors

FTFederica TamburellaDPDiego PiattiSCStefano Filippo Castiglia

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Overview

Prospective longitudinal study shows parallel recovery in neurological and functional outcomes in individuals with cervical SCI, suggesting a phase-specific rehabilitation approach.

Key Points

  • This study aims to understand the timing and sequence of neurological and functional recovery in individuals with cervical spinal cord injury (SCI).
  • Enrolled 21 individuals with incomplete cervical spinal cord injury (AIS C and D).
  • Conducted evaluations every 15 days over a 120-day period.
  • Defined recovery through thresholds for neurological and functional scales.
  • Used survival analysis (Kaplan–Meier) for data analysis.
  • Motor strength improved significantly earlier than sensory recovery.
  • Functional recovery showed significant improvements in parallel with motor strength.
  • No significant differences were found between dominant and non-dominant limbs.

Cite This Study

Tamburella et al. (2026) studied this question.

synapsesocial.com/papers/69ccb66716edfba7beb87fe5https://doi.org/10.3390/jcm15072633
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Spinal Cord Injury Epidemiology and Causes: A Worldwide Analysis with 2050 Projections2025
  2. 2The graded redefined assessment of strength sensibility and prehension version 2 (GV2): Psychometric properties2019 · 19 citations
  3. 3Secondary health conditions and quality of life in persons living with spinal cord injury for at least ten years2016 · 201 citations
  4. 4What do spinal cord injury patients think of their improvement? A study of the minimal clinically important difference of the Spinal Cord Independence Measure III2017 · 25 citations
  5. 5Prediction and Stratification of Upper Limb Function and Self-Care in Acute Cervical Spinal Cord Injury With the Graded Redefined Assessment of Strength, Sensibility, and Prehension (GRASSP)2014 · 55 citations