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High-Level Alzheimer Disease Neuropathological Change Following Iatrogenic Exposure | Synapse

April 1, 2026JAMA Neurology3 citations

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High-Level Alzheimer Disease Neuropathological Change Following Iatrogenic Exposure

GBGargi BanerjeeQueen Mary University of London TMTze How MokUniversity College London Hospitals NHS Foundation Trust HHHarpreet HyareNational Hospital for Neurology and Neurosurgery

Puntos clave

This research aims to explore the neuropathological changes associated with iatrogenic Alzheimer disease (iAD).
Examined histopathological findings in patients diagnosed with iAD.
Compared findings with classical sporadic Alzheimer disease (AD) features.
Patients with iAD exhibited neuropathological changes typical of sporadic AD.
Language involvement emerged as a significant characteristic in the iAD phenotype.

Resumen

These results demonstrate that patients with iAD can have histopathological findings classically found in sporadic AD and that prominent language involvement might be an important phenotypic feature in this AD subtype.

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Cite This Study

Banerjee et al. (Mon,) studied this question.

synapsesocial.com/papers/69ccb66716edfba7beb881ab https://doi.org/https://doi.org/10.1001/jamaneurol.2026.0437