PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
April 1, 2026PLoS ONE0 citationsOpen Access

Untargeted Metabolomics for Early Detection of Preeclampsia

Untargeted metabolomics for the early detection of preeclampsia: A systematic review of human studies

View Full Paper
Ask AI
Bookmark
Share

Authors

CGCelia García-MañasMMMaría Dolores Jara MontesAAAna Cristina Abreu

Discussion

Loading...

Member takes

Overview

Systematic review synthesizes metabolomics biomarkers for early prediction of preeclampsia, suggesting clinical potential.

Key Points

  • The research aims to evaluate metabolomics-based biomarkers for early detection of preeclampsia.
  • Conducted a systematic review following PRISMA guidelines
  • Performed comprehensive searches in multiple databases
  • Included 12 eligible studies using PICO criteria
  • Assessed risk of bias and study quality
  • Extracted data on study characteristics and findings.
  • Identified significant biomarkers such as alanine, lactate, glutamate, and glutamine
  • Metabolites showed heterogeneity across studies with limited overlap
  • Implications for metabolic pathways such as hepatic dysfunction and immune regulation.

Cite This Study

García-Mañas et al. (2026) studied this question.

synapsesocial.com/papers/69ccb69d16edfba7beb88518https://doi.org/10.1371/journal.pone.0339292
View Full Paper
Ask AI
Bookmark
Share