What question did this study set out to answer?

The aim is to evaluate the impact of nanotechnology on periodontal diagnostics, treatment, and safety concerns.

April 1, 20260 citationsOpen Access

Nano Smiles - Revolutionizing Periodontics With Nanotechnology- A Review

1J1*Dr. Vinu Priya P., 2Dr. Jaishree Tukaram Kshirsagar, 3Dr. Mohamed Riyaz J.

Key Points

The aim is to evaluate the impact of nanotechnology on periodontal diagnostics, treatment, and safety concerns.
Reviewed applications of nanotechnology in periodontal therapy.
Analyzed effectiveness of engineered nanoparticles and nano-modified materials.
Examined preclinical and early clinical data on various nano-strategies.
Nanoparticles effectively localize therapeutics and disrupt harmful biofilms.
Early data show promise for antimicrobial nanoparticles and nano-hydroxyapatite grafts.
Concerns persist regarding long-term safety and regulatory standards in nanotechnology applications.

Abstract

Nanotechnology is reshaping periodontal diagnostics, drug delivery, anti-infective strategies, and tissue regeneration. Engineered nanoparticles (NPs), nanofibers, and nano-modified biomaterials can localize therapeutics within periodontal pockets, disrupt biofilms, modulate inflammation, and enhance regeneration through spatiotemporally controlled release of bioactive agents. While preclinical and early clinical data are encouraging-particularly for antimicrobial NPs, nano-hydroxyapatite (nHA) grafts, and nano-enabled membranes-questions remain about long-term safety, standardization, and regulatory pathways.1

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