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Findings reveal a novel relationship between endoplasmic reticulum and connecting cilium rootlet in photoreceptors, suggesting important structural roles.
These findings suggest that the rootlet plays a critical role in organizing intracellular architecture by serving as a kind of "scaffold" that supports ER positioning and allowing it to branch and form membrane contact sites with other cellular membranes.
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Novoselov et al. (2026) studied this question.
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