Advances in the Treatment of Rheumatoid Arthritis

Rheumatoid arthritis (RA) is characterized by synovitis, bone erosion, and cartilage destruction, which ultimately lead to joint destruction. The pyramidal plan, which aims to attenuate symptoms, was the standard treatment for RA. However, advances in therapeutic agents mean that the maintenance of remission is now a realistic treatment goal. Recent treatments, including methotrexate, biological disease-modifying anti-rheumatic drugs, and Janus kinase inhibitors, achieve low disease activity and improve the prognosis of RA; however, not all patients exhibit favorable responses. Furthermore, the economic burden and adverse effects associated with these treatments have not yet been resolved. Therefore, the development of more effective and safer therapies is required. Advances in the treatment of RA have been discussed herein.