Bayesian adaptive trial compares intravaginal magnesium sulfate and IV dexamethasone for labor acceleration, suggesting a safer option.
Intravaginal MgSO4 produced cervical effacement and dilation comparable to IV dexamethasone but achieved a significantly greater reduction in labor duration. Given similar neonatal safety outcomes, these findings suggest that intravaginal MgSO4 may be a preferable first-line agent for labor acceleration.
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Hosseini et al. (2026) studied this question.
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