This review demonstrates the regenerative effects of AdMSC secretome on testicular injury, indicating its therapeutic promise for male infertility.
AdMSC secretome demonstrates therapeutic potential in chemically-induced testicular injury by promoting seminiferous tubule regeneration, reducing apoptosis, and enhancing Leydig cell recovery, with VEGF playing a critical mechanistic role. These findings support the potential AdMSC secretome as a cell-free regenerative approach for male infertility.
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Evangelista et al. (2026) studied this question.
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