PulseExploreJournal ClubResearchersJournals
Instagram
HomeJournal ClubExplore
Synapse
⌘+K
Synapse
April 3, 2026Sleep Medicine ResearchOpen Access

Depressive and Attentional Symptoms in Narcolepsy: Findings From Patients, First-Degree Relatives, and Controls

View Full Paper
Ask AI
Bookmark
Share

Authors

ELEun Hye LeeTKTae-Won KimYKYoung-Chan Kim

Discussion

Loading...

Member takes

Overview

Cross-sectional study explores depression and attention symptoms in narcolepsy patients and their relatives, suggesting familial links.

Key Points

  • This research aims to examine depressive symptoms and ADHD-related traits in narcolepsy patients and their first-degree relatives while considering sleep disturbances.
  • Conducted a cross-sectional study with 613 participants including narcolepsy patients, their relatives, and healthy controls.
  • Measured depressive symptoms using the Beck Depression Inventory-II (BDI-II) and attention traits with the Adult ADHD Self-Report Scale (ASRS).
  • Assessed sleep quality via the Pittsburgh Sleep Quality Index (PSQI) and excessive daytime sleepiness with the Epworth Sleepiness Scale (ESS).
  • Analyzed group differences using ANCOVA while controlling for age, sex, body mass index, PSQI, and ESS.
  • Narcolepsy patients showed significantly higher unadjusted depression scores (mean 27.51) and attentional symptoms (mean 11.47).
  • After adjustment for covariates, patients and their relatives reported higher BDI-II scores compared to controls (F=25.03, p<0.001).
  • Affective-cognitive items on the BDI-II remained elevated after adjustments.
  • The group effect on the ASRS was not significant after controlling for sleep disturbances (F=1.45, p=0.236).

Cite This Study

Lee et al. (2026) studied this question.

synapsesocial.com/papers/69cf5cd15a333a821460a6b9https://doi.org/10.17241/smr.2026.03475
View Full Paper
Ask AI
Bookmark
Share