Comparative study shows no benefit of preoperative biliary drainage in moderately jaundiced patients, suggesting upfront surgery is safer.
In patients with moderate jaundice (10-15 mg/dL), upfront PD can be performed safely. Routine PBD offers no clinical benefit and is associated with higher rates of SSIs, bile contamination, and increased costs.
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Rathore et al. (2026) studied this question.
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