Association of Hyperlipidemia on the Prevalence and Risk Factors of Kidney Stones and Hypertension

Background This study aimed to assess the risk of kidney stones in a hyperlipidemic population and explore the development risk and related indicators with or without hypertension. Methods A cross‐sectional study included 1000 hyperlipidemic patients from Nanshan District Medical Group Headquarters, Shenzhen, 2021. Measurements covered BMI, blood pressure, renal function, and urinalysis. Descriptive statistics, group comparisons, and a logistic regression model were used, with p < 0.05 for significance. Results Among 1000 hyperlipidemic patients, 23.3% had hypertension, and the kidney stone prevalence was 15.4%. Double kidney stones were more common in the hypertensive group (40.6%). Logistic regression showed that males, elevated blood urea nitrogen, and positive glycosylated hemoglobin were independent risk factors for kidney stones. In the hypertension–hyperlipidemia subgroup, a higher stone prevalence was noted in those patients aged 60–69 years (OR = 2.92, 95% CI: 1.04–8.20, p = 0.014) and elevated blood creatinine (OR = 4.47, 95% CI: 1.36–14.65, p = 0.040). After adjustment, elevated blood creatinine remained an independent risk factor. Conclusions The kidney stone prevalence in hyperlipidemic patients was 15.4%. Age, gender, blood creatinine, urea nitrogen, and glycosylated hemoglobin are key factors for kidney stone development.