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April 3, 2026DiagnosticsOpen Access

Dominant Temporo-Basal Glioblastoma with Rapid Progressive Aphasia: Venous-Anchored Maximal Safe Resection and Quantified Language Recovery

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Authors

VGValentin Titus GrigoreanADAdrian Vasile DumitruNDNicolaie Dobrin

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Overview

Case study reports language recovery in a patient with dominant temporo-basal glioblastoma, suggesting effective surgical techniques.

Key Points

  • The study aims to demonstrate effective surgical interventions for glioblastomas in the dominant hemisphere to preserve language functions.
  • Anatomically defined imaging techniques were used to assess tumor location.
  • Venous-anchored microsurgery was performed to tread carefully around eloquent cortical areas.
  • Continuous intraoperative monitoring using SSEPS/MEPs guided surgical decisions.
  • Postoperative assessments included NIHSS, MoCA, BNT, SF, mRS, BI, and IADL.
  • Postoperative scans indicated stable decompression with no hemorrhage.
  • Quantitative improvement in NIHSS scores from 8 to 2 and MoCA scores from 18 to 26 was observed.
  • Language capabilities improved significantly with BNT scores rising from 8 to 26 and SF from 4 to 12.
  • Functional independence improved as mRS decreased from 4 at admission to 1 at follow-up.

Cite This Study

Grigorean et al. (2026) studied this question.

synapsesocial.com/papers/69cf5d775a333a821460b373https://doi.org/10.3390/diagnostics16071057
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