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April 3, 20260 citationsOpen Access

Impact of learning curve on outcomes of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in colorectal cancer patients at a specialized center.

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VAVural ArgınÖÖÖmer ÖzdumanASAhmet Orhan Sunar

Key Points

  • To evaluate the impact of the learning curve on perioperative outcomes in colorectal cancer surgeries.
  • Analyzed outcomes of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy procedures
  • Monitored changes in transfusion requirements and operative time with increased experience
  • Assessed the extent of resection in relation to surgical expertise
  • Increased surgical experience correlated with reduced intraoperative transfusion rates
  • Operative time decreased as the learning curve progressed
  • Improvement in the extent of surgical resection observed, but no survival benefit noted

Abstract

The learning curve significantly influences perioperative outcomes in cytoreductive surgery and hyperthermic intraperitoneal chemotherapy procedures. As surgical experience increases, intraoperative transfusion requirements and operative time decrease, while the extent of resection improves. However, these improvements do not appear to translate into a survival benefit.

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Cite This Study

Argın et al. (2026) studied this question.

synapsesocial.com/papers/69cf5dd55a333a821460bd5ehttps://doi.org/10.1590/1806-9282.20250905
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