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April 3, 2026Discover Nano0 citationsOpen Access

Biofilm Disruption on Root Dentin Using Conventional and Nanoparticle-Enhanced Photodynamic...

Evaluation of biofilm disruption on root dentin following conventional and nanoparticle-enhanced photodynamic therapies using scanning electron microscopy and FIJI-based image analysis

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Authors

RJRizwan JouharMHMohamad Syahrizal HalimSQSayed A. QuadriKing Faisal University

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Overview

Evaluation of biofilm disruption in root dentin using different disinfection protocols, suggesting enhanced endodontic treatment.

Key Points

  • This study aims to evaluate the effectiveness of various disinfection protocols against Enterococcus faecalis biofilm on root canal dentin.
  • Analyzed biofilm disinfection protocols including sodium hypochlorite, photodynamic therapy with methylene blue, and MB-rGO nanoparticles.
  • Used scanning electron microscopy (SEM) and FIJI software for image analysis.
  • Inoculated root dentin specimens with E. faecalis to cultivate mature biofilms for 21 days.
  • Employed a longitudinal sectioning approach to prepare standardized dentin specimens for various treatment groups.
  • Applied statistical analysis with one-way ANOVA and Tukey’s post hoc test.
  • NaOCl-treated groups showed moderate biofilm reduction (35.57% and 31.67%).
  • PDT with methylene blue resulted in greater reduction but was less effective than NaOCl.
  • MB-rGO groups exhibited the highest efficacy, particularly with sonic activation in Group 6, which had a significant reduction (10.46%).
  • Quantitative and semi-quantitative analyses confirmed that Group 6 had the lowest biofilm coverage score (1.20).

Cite This Study

Jouhar et al. (2026) studied this question.

synapsesocial.com/papers/69cf5e745a333a821460cd46https://doi.org/10.1186/s11671-026-04542-5
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