Acute response to a high-fat-high-refined carbohydrate meal in healthy young men shows novel perturbation of multiple metabolic and defense pathways

Key Points

• This research aims to explore how healthy young men respond to a high-fat, refined carbohydrate meal and the effects on their metabolic flexibility.
• Analyzed blood markers before and after a high-fat, refined carbohydrate meal.
• Examined rapid changes in metabolic response.
• Identified perturbations in various metabolic and defense pathways.
• Metabolic flexibility showed significant changes after the meal.
• Multiple metabolic and defense pathways were affected.
• Responses highlighted a deviation from normal adaptability.