Endocervical gastric‐type AIS : a rare histologic finding that further supports the hypothesis of a pyloric‐type metaplastic origin

Michele Paudice; Veronica Parrella; Giulia Scaglione

doi:10.1111/his.70150

April 1, 2026HistopathologyOpen Access

Endocervical gastric‐type AIS : a rare histologic finding that further supports the hypothesis of a pyloric‐type metaplastic origin

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Key Points

To explore the potential relationship between gastric-type AIS and pyloric-type gastric metaplasia.
Case analysis of gastric-type AIS in endocervical tissue
Histological examination to identify pyloric-type metaplasia
Comparison of histological features in cervical lesions
Identified a case of gastric-type AIS with pyloric-type features
Strengthened the hypothesis of a metaplastic origin
Noted implications for accurate diagnosis in HPV-independent lesions

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Implication

Case supports a link between genetic AIS and pyloric-type gastric metaplasia, suggesting important diagnostic implications.

Abstract

This case supports a possible link between gAIS and pyloric-type gastric metaplasia, underscoring the importance of accurate recognition in HPV-independent cervical lesions.

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Paudice et al. (2026) studied this question.

synapsesocial.com/papers/69cf5eee5a333a821460da0c https://doi.org/10.1111/his.70150

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Endocervical gastric‐type AIS : a rare histologic finding that further supports the hypothesis of a pyloric‐type metaplastic origin

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Endocervical gastric‐type AIS : a rare histologic finding that further supports the hypothesis of a pyloric‐type metaplastic origin

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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