Key result
Sustaining DBP above current clinical thresholds is feasible during prolonged pediatric in-hospital CPR.
Cohort (n=118)
No
Achieving higher, time-dependent diastolic blood pressure thresholds during prolonged pediatric in-hospital cardiac arrest is associated with increased odds of return of spontaneous circulation.
Maintain current DBP targets in prolonged pediatric CPR; leaves open if higher patient-specific targets improve ROSC, larger studies needed.
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Loaec et al. (2026) conducted a cohort in Pediatric in-hospital cardiac arrest (n=118). Higher diastolic blood pressure thresholds (≥30 mm Hg in infants and ≥35 mm Hg in children) vs. Lower diastolic blood pressure thresholds was evaluated on Return of spontaneous circulation (ROSC) in prolonged CPR (≥ 10 min) (OR 7.14, 95% CI 1.58-51.35, p=0.009). Achieving higher diastolic blood pressure thresholds later in prolonged pediatric CPR was associated with return of spontaneous circulation (OR 7.14; 95% CI 1.58-51.35; p=0.009).
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