Functional implications of lesion morphology in untreated osteochondral lesions of the talus

These findings indicate that lesion surface area is a stronger predictor of functional impairment than lesion location or depth in the untreated state of non-surgically treated OLT. The results underscore the value of quantitative lesion assessment in the nonsurgical management of talus osteochondral defects and suggest that MRI-based lesion area measurements may help to characterize functional impairment in patients with untreated OLT.