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Multicohort mega-analysis reveals alterations in amygdala and hippocampus connectivity in PTSD, implying significant neurological changes.
Studies investigating resting-state functional connectivity of the amygdala and hippocampus have produced inconsistent findings. The authors’ objective was to conduct the largest systematic comparison of alterations in functional connectivity of the amygdala and hippocampus in individuals with posttraumatic stress disorder (PTSD) using a multicohort mega-analysis with uniform processing steps and parameters across all cohorts.
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Hinojosa et al. (2026) studied this question.
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