Cardiomyocytes express most known Toll-like receptors. Of these, TLR2, TLR4 and TLR5 signal via NF-kappaB, resulting in decreased contractility and a concerted inflammatory response.

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Boyd et al. (Sun,) studied this question.

synapsesocial.com/papers/69cfa8f632950d6ce7347eb0 https://doi.org/https://doi.org/10.1016/j.cardiores.2006.09.011

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Toll-like receptor stimulation in cardiomyoctes decreases contractility and initiates an NF-κB dependent inflammatory response☆ | Synapse

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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